Anticariogenic Effect of Glycyrrhiza uralensis Extract on Oral Disease Bacteria
- Conditions
- Not Applicable
- Registration Number
- KCT0006998
- Lead Sponsor
- Kangwon National University
- Brief Summary
The use of the mouthwash containing Glycyrrhiza uralensis extract significantly decreased the clinical values in all parameters of O'Leary index, PI, and GI (p<0.05). Also, after gargling mouthwash containing Glycyrrhiza uralensis, the antibacterial effect on Gram-positive and Gram-negative bacteria that cause periodontal disease was confirmed to have excellent clinical effects in the inhibition, prevention, and treatment of periodontal disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
The subjects of this study were patients who agreed to complete the questionnaire, were not included in the exclusion criteria, and had 16 or more remaining teeth.
Among the study subjects, those with severe dental disease (e.g., periodontitis, dental caries, dry mouth, etc.) (patients with enamel caries among dental caries are eligible to participate in the study, with the exception of patients with more than one dentine caries), those who are undergoing treatment for general disease that may cause oral odor (e.g., hepatic disease, renal disease, Sjogren's syndrome, and rheumatism), those who smoke, those who have been diagnosed with sinusitis and/or rhinitis, those who are taking antibiotics, those with tongue problems (e.g., tongue cancer, glossitis, etc.), and those who received scaling within 2 months correspond to the exclusion criteria and were excluded from this study.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method microbiological analysis
- Secondary Outcome Measures
Name Time Method O’Leary index ;Plaque index (PI) ;Gingival index (GI)