NL-OMON50261招募中4 期
Partial neuromuscular blockade to facilitate lung and diaphragm protective mechanical ventilation in ICU patients: A randomized controlled pilot study. - Partial neuromuscular blockade for lung protective mechanical ventilation
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- high respiratory drive, defined as tidal volume > 8ml/kg PBW on inspiratory
- •support of 12cmH2O.
- •- sedation level: RASS <= -3
- •- ventilated in pressure support mode
排除标准
- •- recent use of NMBA (<2 hrs)
- •- arterial pH <7.25
- •- hemodynamic instability, i.e. high dose vasopressors (>0.5 µg/kg/min) or
- •inotropes (dobutamine >15 µg/kg/min or enoximone >25 µg/kg/min)
- •- intracranial pressure >20 cmH2O
- •- past medical history of neuromuscular disorders
- •- pregnancy
- •- known previous anaphylactic reaction to NMBA*s.
研究者
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