EUCTR2018-000748-24-NL进行中（未招募）1 期
Partial neuromuscular blockade to facilitate lung and diaphragm protectivemechanical ventilation in ICU patients.A randomized controlled pilot study.
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- VUmc
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Patients are eligible for inclusion if they meet all of the following
- •- high respiratory drive, defined as tidal volume > 8ml/kg PBW on
- •inspiratory support of 12cmH2O.
- •- sedation level: RASS = -3
- •- ventilated in pressure support mode
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 15
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 15
排除标准
- •A potential subject who meets any of the following criteria will be
- •excluded from participation in this study:
- •- recent use of NMBA (< 2 hrs)
- •- arterial pH < 7.25
- •- hemodynamic instability, i.e. high dose vasopressors (>0.5 µg/kg/min)
- •or inotropes (dobutamine >15 µg/kg/min or enoximone >25
- •- intracranial pressure > 20 cmH2O
- •- past medical history of neuromuscular disorders
- •- pregnancy
- •- known previous anaphylactic reaction to NMBA's.
研究者
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