Skip to main content
Clinical Trials/NCT04966572
NCT04966572
Unknown
Not Applicable

Short Term Efficiency of Presurgical Vacuum Formed Nasoalveolar Molding Aligners in Infants With Bilateral Cleft Lip and Palate Compared With Conventional Grayson Acrylic Formed Nasoalveolar Molding Appliances: A Randomized Clinical Trial

Cairo University1 site in 1 country24 target enrollmentMarch 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cleft Lip and Palate
Sponsor
Cairo University
Enrollment
24
Locations
1
Primary Endpoint
Changes in the maxillary arch
Last Updated
4 years ago

Overview

Brief Summary

Newborns with bilateral cleft lip/ palate will be treated pre-surgically by either presurgical vacuum-formed nasoalveolar molding aligners VF (NAM) or conventional Grayson acrylic formed nasoalveolar molding appliances in order to evaluate their effect on the maxillary arch.

Detailed Description

The aim of this trial is to evaluate and compare the short-term effect of VF (NAM) aligners with conventional Grayson appliances at 2 stages T1 (Before NAM therapy), and T2 (After NAM therapy) as regards maxillary arch changes. Newborns with Bilateral cleft lip/ palate will be allocated randomly into two groups: the first group will receive presurgical vacuum-formed nasoalveolar molding aligners while the second group will receive conventional Grayson acrylic formed nasoalveolar molding appliances. The follow-up period will be 4-6 months till surgical lip closure. The changes in the maxillary arch will be assessed by digital maxillary models.

Registry
clinicaltrials.gov
Start Date
March 1, 2021
End Date
March 30, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Khadega Ali Al Khateeb

Phd student, faculty of Dentistry, Cairo university

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Non-syndromic Infants with complete BCLP infants
  • Infants less than 1 month of age
  • Males and females.
  • Infants with displaced premaxilla
  • Patients whose parents provided written consent for the study.

Exclusion Criteria

  • Patients above 1 month of age
  • Syndromic and systemically ill infants.
  • Patients with unilateral cleft lip and palate.
  • Incomplete Cleft lip.
  • Medically compromised patients
  • Patient's/guardians who will be unwilling to go through the PNAM therapy

Outcomes

Primary Outcomes

Changes in the maxillary arch

Time Frame: T1 and T2 (4- 6 months)

they will be measured in mm by digital models

Study Sites (1)

Loading locations...

Similar Trials