Cognitive and motor training in mild cognitive impairment: an MRI study
Not Applicable
Completed
- Conditions
- F06.7Mild cognitive disorder
- Registration Number
- DRKS00007858
- Lead Sponsor
- niversitätsklinik für Neurologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 61
Inclusion Criteria
MCI
Exclusion Criteria
- Probable dementia,
- History of severe diseases such as stroke or psychiatric disease,
- Treatment with antipsychotics and antidepressants,
- The existence of a relevant depressive mode with a value above 13 by the Beck Depression Inventory
- Unstable medical conditions
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Episodic memory performance:<br><br>At the beginning and at the end of the training phase is detailed neuropsychological testing by VLMT (Verbal learning and memory test)
- Secondary Outcome Measures
Name Time Method - BDNF plasma levels by ELISA:<br>At the beginning and at the end, and once after training<br><br>- Identification of the hippocampus volume by MRI:<br>at the beginning, after completion of the initial training period at 3 months and 6 months.<br><br>- Test for Attentional Performance: Rey-Osterrieth figure, logo test number range and block span, Verbal Fluency, Boston Naming Test, Trail-Making Test A and B, TAP