Brain activation during sentence processing in Parkinson's disease: an event related functional magnetic resonance imaging study

Completed

• Conditions: Parkinson's disease; Nervous System Diseases; Extrapyramidal and movement disorders

• Registration Number: ISRCTN18548326
• Lead Sponsor: niversity of Groningen (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-12-28
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

1. Idiopathic Parkinson's disease (PD)
2. Hoehn and Yahr stage 1 to stage 3
3. Normal vision and hearing
4. Able to give informed consent
5. Older than 40 years
6. Dutch as first language
7. Right-handed
8. Normal structural magnetic resonance imaging (MRI) scan

Exclusion Criteria

1. Not optimally medicated
2. Neurostimulator
3. Implanted pump (e.g. apomorphine)
4. Dementia (Mini Mental State Examination [MMSE] score less than 25)
5. Depression (Montgomery-Asberg Depression Rating Scale [MADRS] more than 18)
6. Another neurological disease
7. Another akinetic-rigid disorder
8. Another movement disorder
9. No normal structural MRI scan

Study & Design

• Study Type: Observational
• Study Design: Not specified