PREVENTION OF VASOPLEGIA WITH THE USE OF CYTOSORB
Recruiting
- Conditions
- Vasoplegia - Low blood pressure100192801000759310011954
- Registration Number
- NL-OMON55069
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 36
Inclusion Criteria
-Diagnosed with heart failure (HF) in line with the European Society of
Cardiology (ESC)
guidelines
-Left ventricular ejection fraction (EF) <=35%
-Undergoing cardiac surgery on cardiopulmonary bypass (CPB) with an anticipated
duration of at least 120 minutes
-Age >= 18 years.
Exclusion Criteria
-Incapacitated
-Emergency operation
-Need for moderate or high dosages of intravenous inotropic support (>4 gamma
dobutamine or dopamine) and/or vasopression;
-Severe tricuspid regurgitation;
-Daily use of nitroglycerine or isosorbide dinitrate
-Use of alpha blockers
-Being Heparin Induced Thrombocytopenia (HIT) positive and citrate regional*
anticoagulation is unavailable as an alternative anticoagulation method
-Platelet count < 20,000/µL.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- Change in systemic vascular resistance index after phenylephrine<br /><br>administration (delta SVRi) after CPB;<br /><br>- Reduction in the occurrence of Vasoplegic Syndrome (VS).</p><br>
- Secondary Outcome Measures
Name Time Method