Effect of Anesthesia on Frontal QRS t Angle in Obese Individuals

Completed

• Conditions: Obesity and Obesity-related Medical Conditions

• Registration Number: NCT07034001
• Lead Sponsor: Amasya University

Brief Summary

The aim of this observational study is to determine the effect of anesthesia on frontal qrs-t angle changes in obese individuals. To learn the long-term effects of intervention A in individuals with a body mass index \> 30 who received intervention A. The main question it aims to answer is:

Does frontal qrs-t angle change occur in obese individuals due to anesthesia? Preoperative and intraoperative ECG changes of individuals undergoing surgery will be examined.

Detailed Description

All patients were routinely administered 500 cc of Ringer's lactated solution intravenously (IV) before anesthesia and taken to the operating room. The body mass index will be calculated according to the formula body weight kg / height cm2. Obese patients with a BMI above 30 kg/m2 were recorded as group 2, and non-obese patients with a BMI below \<30 kg/m2 were recorded as group 1. Patients were taken to the operating room and routine ECG, noninvasive blood pressure, pulse, and oxygen saturation monitoring (CARESCAPE™ B650, GE Healthcare, USA) was performed. All patients were hydrated intravenously (IV) with 500 cc of Ringer's lactated solution after a 6-hour fast. For premedication, midazolam 1 mg IV and pantoprazole 40 mg IV were administered. For anesthesia induction, propofol 2 mg/kg, fentanyl 2 mg/kg and rocuronium 0.6 mg/kg were administered intravenously.

Study Timeline

• Study Start: 2024-12-01
• Primary Completion: 2025-04-30
• Study Completion: 2025-05-10
• Status Verified: 2025-06
• Study First Submitted: 2025-06-15
• Study First Submitted QC: 2025-06-15
• Last Update Submitted: 2025-06-15
• Study First Posted: 2025-06-24
• Last Update Posted: 2025-06-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 93

Inclusion Criteria

• People between the ages of 18-65 who underwent laparoscopic cholecystectomy surgery

Exclusion Criteria

• known coronary artery disease, atrial fibrillation, heart failure, liver failure, kidney failure, preexcitation syndromes, electrolyte disorders, use of drugs that prolong the QT interval, respiratory failure and metabolic diseases were excluded from the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frontal qrs-t angle	1 day	Frontal qrs t angle examination on ecg
EKG	1 day	Frontal qrs t angle and qt interval examination on ecg

Trial Locations

Locations (1)

Amasya University; 🇹🇷 Amasya, Turkey