Comparison Between The Analgesic Effect of Oblique Subcostal and Lateral Approach of Ultrasound-Guided Transverse Abdominis Blocks for Patients Undergoing Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- opioid consumption
研究概览
简要总结
the investigators will compare the effect of pre-operative oblique subcostal TAP and lateral TAP blocks on the total perioperative opioids consumption for patients undergoing elective laparoscopic cholecystectomy
详细描述
General anesthesia induction will be achieved using a sleeping dose of fentanyl 1µg/kg intravascular(IV), propofol 2mg/kg (IV), and atracurium 0.5mg/kg (IV) to facilitate tracheal intubation. General anesthesia will be maintained with lungs ventilation by pressure controlled mode with isoflurane
During anesthesia maintenance Intraoperatively, if blood pressure BP or heart rate (HR) increase more than 20% from baseline, intravenous morphine (3- 5mg) will be given to stabilize the patients' haemodynamics. Fifteen minutes before the end of surgery all patients will receive 1g intravenous paracetamol and 4 grams ondansetron.
Patients will be randomly divided into three equal groups:
Group A: will receive bilateral oblique subcostal TAP block Group B: will receive bilateral lateral TAP block. Group C :will receive postoperative morphine by patient-controlled analgesia (PCA).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Eligible patients will be older than 21 years old with American society of anaesthesia physical status I& II scheduled for elective laparoscopic cholecystectomy.
排除标准
- •- Uncooperative.
- •Patients who have allergy to any of the study drugs.
- •Patients who are on opioids.
- •Known abuse of alcohol or medication.
- •Local infection at the site of injection or systemic infection.
- •Pregnancy.
- •Patients with coagulation disorders or on anticoagulation therapy.
结局指标
主要结局
opioid consumption
时间窗: 48 hours
milligrams
次要结局
- patient satisfaction(48 hours)
- total perioperative analgesics requirements(24 hours)
- anesthesia recovery time(1hour)
- Post-operative anaesthetic care unit (PACU) stay(2 hours)
研究者
Amal Gouda Elsayed Safan
Lecturer of Anesthesiology, Intensive Care and Pain Management Faculty of Medicine - Menoufia University
Menoufia University