The Effect of Integrated Care Involving Peripheral Functional Magnetic Stimulation and Nutritional Supplement for Age-related Sarcopenia
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Handgrip strength
Study Overview
Brief Summary
The goal of this clinical randomized trial is to test whether an integrated care involving peripheral functional magnetic stimulation and nutritional supplement is beneficial in population with age-related sarcopenia, as compared to usual care.
Detailed Description
We will recruit participants with sarcopenia or possible sarcopenia. The participants will be divided into 2 groups. One group, the "integrated care" group, will receive both the peripheral functional magnetic stimulation to both the upper and lower limbs and nutritional supplement for consecutive 8 weeks. The other group, the "usual care" group, will receive an educational digital versatile disc (DVD) and a handbook for exercise suggestions on sarcopenia. We will compare before and after the intervention about the body composition, handgrip strength, 5-time chair stand test, 6-meter walk, and blood test for C-reactive protein and other cytokines related to sarcopenia. The participant's nutritional condition, activity level, life quality will also be analyzed via questionnaires before and after the intervention.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 65 Years to 90 Years (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age from 65 to 90
- •Can walk independently for over 15 minutes
- •Diagnosed with possible sarcopenia or sarcopenia (by Asian Working Group for Sarcopenia: 2019 Consensus Update onSarcopenia Diagnosis and Treatment)
Exclusion Criteria
- •Cognitive impairment
- •History of cerebrovascular disease
- •Deep vein thrombosis
- •Malignancy under treatment
- •Coagulopathy
- •Serious orthopedic condition over limbs
- •Inability to walk independently without assistive device
- •Any other conditions not suggested to performance exercise
- •Medical implants (e.g. pacemaker, defibrillator, deep brain nerve stimulation, infusion pump, etc.)
Outcomes
Primary Outcomes
Handgrip strength
Time Frame: Before the intervention, and 1-2 weeks after the 8-week intervention
We use a dynamometer to measure the handgrip strength (kg)
5-time chair stand test
Time Frame: Before the intervention, and 1-2 weeks after the 8-week intervention
We measure the time of a subject to transfer from a seated to a standing position and back to sitting five times.
Body composition
Time Frame: Before the intervention, and 1-2 weeks after the 8-week intervention
We use dual energy x-ray absorptiometry to evaluate the muscle mass (kg/m2) in the subjects.
6-meter walk
Time Frame: Before the intervention, and 1-2 weeks after the 8-week intervention
We measure the time of a subject to walk with the usual speed straightly for 6 meters.
Secondary Outcomes
- Leg circumference(Before the intervention, and 1-2 weeks after the 8-week intervention)
- Nutritional status(Before the intervention, and 1-2 weeks after the 8-week intervention)
- Cytokines related to sarcopenia(Before the intervention, and 1-2 weeks after the 8-week intervention)
- Life quality(Before the intervention, and 1-2 weeks after the 8-week intervention)
- Activity level(Before the intervention, and 1-2 weeks after the 8-week intervention)