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Clinical Trials/DRKS00034597
DRKS00034597
Not Yet Recruiting
N/A

High flow oxygen therapy with automatic closed-loop controlled oxygen titration in hypoxemic respiratory failure: a randomized-controlled trial.

Klinik für Anästhesiologie, operative Intensivmedizin und Schmerzmedizin, Universitätsmedizin Mannheim0 sites150 target enrollmentJuly 3, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
J96.9
Sponsor
Klinik für Anästhesiologie, operative Intensivmedizin und Schmerzmedizin, Universitätsmedizin Mannheim
Enrollment
150
Status
Not Yet Recruiting
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 3, 2024
End Date
TBD
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
Klinik für Anästhesiologie, operative Intensivmedizin und Schmerzmedizin, Universitätsmedizin Mannheim

Eligibility Criteria

Inclusion Criteria

  • Patients with hypoxemic respiratory failure admitted to IMC ward 37\-4 or ICU 32\-3
  • \- Need for HFOT with \= 40 L/min with a FiO2 \= 0\.30
  • \- HFOT foreseeable on admission for at least 24 hours

Exclusion Criteria

  • \- Age \= 18 years
  • \- Pregnancy
  • \- Expected or present dyshemoglobinemia
  • \- Poor signal quality of SpO2 measurement at finger and ear (quality index \< 60%)
  • \- Haemodynamic instability (noradrenaline or adrenaline with a necessary continuous infusion of \> 1 mg/h)
  • \- Severe respiratory acidosis with pH \< 7\.25
  • \- Difference between SpO2 and SaO2 of more than 5%

Outcomes

Primary Outcomes

Not specified

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