Comparison efficacy of Chlorthalidone and Hydrochlorothiazide for the treatment of systemic hypertensio

Phase 4

• Conditions: Hypertensive patients; Chlorthalidone; Hydrochlorothiazide; Efficacy; Hypertension

• Registration Number: TCTR20191006002
• Lead Sponsor: Berlin Pharmaceuticals

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-10-06
• Study Completion: 2020-10-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

Age > 18 years
Newly diagnosed or known hypertension (BP > 140/90 mmHg)

Exclusion Criteria

Secondary hypertension
Curable hypertension
History of previous diuretic use
ALT > 2X UNL
Cr > 1.5 mg/dl
SBP > 180/110 mmHg
Participants in other study
Pregnancy
Unable to follow-up
History of gout or serum uric acid > 10 mg/dl

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease in systolic blood pressure, number of patients that achieved blood pressure goal baseline, 6 week, 12 week Automatic blood pressure measurement

Secondary Outcome Measures

Name	Time	Method
Drug side effect baseline, 6 week, 12 week Blood chemistry measurement, patient's symptom