Platelet Rich Plasma Testis Treatment for Infertile Men
Not Applicable
Recruiting
- Conditions
- Male InfertilityNonobstructive AzoospermiaAzoospermia
- Interventions
- Biological: Platelet rich plasma
- Registration Number
- NCT05479474
- Lead Sponsor
- Stanford University
- Brief Summary
Investigate the effect of intratesticular injection of autologous platelet rich plasma (PRP) on sperm retrieval rates and IVF outcomes in infertile men who already underwent a negative sperm retrieval. Currently, there is no alternative treatment after failed TESE. Prior series suggest that intratesticular PRP injections may improve TESE outcomes. We hope to determine whether PRP is an effective treatment for this patient population.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Male
- Target Recruitment
- 10
Inclusion Criteria
- Men over the age of 18 diagnosed with NOA and at least one failed TESE, negative mapping or negative biopsy
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Exclusion Criteria
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Platelet rich plasma treatment arm Platelet rich plasma After consent in obtained, the patient will undergo a blood draw (12 tsp) to prepare the PRP infusion. The use of a centrifuge and an Arteriocyte Magellan kit are necessary for the PRP preparation. After injection of local anesthesia, PRP will be injected into each testicle.
- Primary Outcome Measures
Name Time Method sperm present 3 months after PRP injection A TESE procedure will be performed to determine if sperm are present
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Stanford Urology Clinic
🇺🇸Stanford, California, United States