Effect of Nutrition on Treatment of Tuberculosis Diseases

Not Applicable

• Registration Number: CTRI/2019/05/018968
• Lead Sponsor: Warren Alpert Foundation Boston Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Household contact that has been roommate of eligible index case for at

least two of the previous four months (See index case criteria below).

2. HIV seronegative

3. Willing to be tested for pregnancy

4. Age 18-55 years

5. Willingness by the patient to attend scheduled follow-up visits and undergo

study assessments

6. Able to provide informed consent

Exclusion Criteria

1. In the teamâ??s judgement, individual is not expected to survive for 12

months

2. HIV infection or not willing to undergo HIV testing (if no documented HIV

test)

3. Pregnant at enrollment

4. Known diabetes mellitus or evidence of diabetes on HA1C

5. Xpert positive among those able to produce sputum

6. TB symptoms (night sweats, weight loss, cough)

7. Any history of TB disease during their lifetime

8. We will retrospectively exclude household contacts of presumed TB cases

whose cultures do not confirm Mtb or who are Xpert negative.

9. Recall receiving anti-parasitic treatment within the past 6 months

10. Evidence of kwashiorkor (pitting edema of foot or lower leg)

11. Abnormal K, Mg, Phos in those with BMI <16

Study & Design

• Study Type: Interventional
• Study Design: Not specified