Dietary Assessment and Prevalence of Refeeding Syndrome in High-risk TB Patients in Chhattisgarh, India

Completed

• Conditions: Severe Malnutrition; Tuberculosis; Refeeding Syndrome

• Registration Number: NCT03537170
• Lead Sponsor: Washington University School of Medicine

Brief Summary

Severe tuberculosis (TB) leads to wasting and anorexia, increasing risk of the refeeding syndrome (RFS) as defined by current criteria. TB patients have high metabolic rates and require a high calorie diet, with nutritional supplementation programs improving outcomes. BMI inversely correlates with mortality in these patients. Risk of RFS, a life-threatening syndrome associated with initiation of feeding after a period of low intake, has not been studied in this population and it is not known whether severely malnourished TB patients benefit from lower caloric intake. This study aimed to examine the prevalence of RFS in TB inpatients in rural India and correlate this with baseline and inpatient caloric intake.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-11-23
• Primary Completion: 2018-02-14
• Study Completion: 2018-02-14
• Status Verified: 2018-05
• Study First Submitted: 2018-05-11
• Study First Submitted QC: 2018-05-23
• Last Update Submitted: 2018-05-23
• Study First Posted: 2018-05-25
• Last Update Posted: 2018-05-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

• all adult inpatients admitted to the TB ward
• able to take enteral intake

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Exclusion Criteria

• unable to take enteral intake

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Inpatient caloric intake	from date of admission to discharge, up to 100 weeks

Secondary Outcome Measures

Name	Time	Method
Incidence of refeeding syndrome	from date of admission to discharge, up to 100 weeks

Trial Locations

Locations (1)

Jan Swasthya Sahyog; 🇮🇳 Ganiyari, Chhattisgarh, India