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A study to find an alternative parameter to guide infusion of intravenous fluid in liver resectio

Not Applicable
Completed
Conditions
Health Condition 1: null- Adult patients undergoing hepatic resections(2 segments)Health Condition 2: D134- Benign neoplasm of liverHealth Condition 3: C23- Malignant neoplasm of gallbladderHealth Condition 4: C22- Malignant neoplasm of liver and intrahepatic bile ducts
Registration Number
CTRI/2018/01/011547
Lead Sponsor
PGIMER
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

All adult patients scheduled for open, elective hepatic resection (>= 2 segments). The group will also include patients who are initially approached laparoscopically but converted to an open resection. Patients undergoing additional procedures will also be assessed for eligibility.

Exclusion Criteria

Active coronary artery disease or congestive heart failure, Atrial fibrillation or flutter,

Acute renal dysfunction, severe portal hypertension, Pregnancy, Extreme Body mass index (BMI) >45 OR < 17, Significant pulmonary insufficiency

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
â?¢To compare Pressure Variation(PPV) as an alternative to Low Central Venous Pressure(LCVP) guided approach in order to reduce blood loss during hepatic resectionsTimepoint: 30th July 2018
Secondary Outcome Measures
NameTimeMethod
â?¢To compare arterial lactate levels during different phases of liver resection. <br/ ><br> <br/ ><br>Timepoint: 1 day post operatively
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