A study to find an alternative parameter to guide infusion of intravenous fluid in liver resectio
- Conditions
- Health Condition 1: null- Adult patients undergoing hepatic resections(2 segments)Health Condition 2: D134- Benign neoplasm of liverHealth Condition 3: C23- Malignant neoplasm of gallbladderHealth Condition 4: C22- Malignant neoplasm of liver and intrahepatic bile ducts
- Registration Number
- CTRI/2018/01/011547
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
All adult patients scheduled for open, elective hepatic resection (>= 2 segments). The group will also include patients who are initially approached laparoscopically but converted to an open resection. Patients undergoing additional procedures will also be assessed for eligibility.
Active coronary artery disease or congestive heart failure, Atrial fibrillation or flutter,
Acute renal dysfunction, severe portal hypertension, Pregnancy, Extreme Body mass index (BMI) >45 OR < 17, Significant pulmonary insufficiency
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method â?¢To compare Pressure Variation(PPV) as an alternative to Low Central Venous Pressure(LCVP) guided approach in order to reduce blood loss during hepatic resectionsTimepoint: 30th July 2018
- Secondary Outcome Measures
Name Time Method â?¢To compare arterial lactate levels during different phases of liver resection. <br/ ><br> <br/ ><br>Timepoint: 1 day post operatively