Diagnostic approaches in patients clinically suspected of Ischemic Colitis (IC).
Recruiting
- Conditions
- Ischemic Colitis
- Registration Number
- NL-OMON20037
- Lead Sponsor
- Erasmus MC, University Medical Center Rotterdam, The Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1. All patients older than 18 years old with acute onset of abdominal pain with diarrhea with or without blood loss and clinical indication for (ileo-)colonoscopy;
2. Informed consent.
Exclusion Criteria
1. Known and recently inflammatory bowel disease in medical history;
2. Infectious colitis;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary endpoint:<br /><br>The evaluate the diagnostic value of mucosal oxygen saturation measurement to endoscopy and histological examination.<br><br>
- Secondary Outcome Measures
Name Time Method Secondary endpoints:<br /><br>1. To evaluate whether detection of hypoxia dependent molecular changes in the mucosa can be used to improve sensitivity of histological analyses;<br /><br>2. To evaluate whether Doppler US of the abdomen can improve differentiation between patients with IC and other causes of abdominal pain and diarrhea.<br>