Comparison of Dexmedetomidine with Magnesium Sulphate for preventing the increase in blood pressure and heart rate that occur at the time of endotracheal tube insertion in adult patients
- Conditions
- AGE 18-60YEARS OF EITHER SEX, ASA GRADE I AND II
- Registration Number
- CTRI/2018/04/012985
- Lead Sponsor
- Vardhman Mahavir Medical College and Safdarjung Hospital New Delhi
- Brief Summary
1) To compare the efficacy of infusion Dexmedetomidine with magnesium sulphate on haemodynamic parameters during endotracheal intubation in adult patients
2) To study the effect of dexmedetomidine & magnesium sulphate infusion on post operative sedation, requirement of neuromuscular blocking agent & recovery characteristics.
Hypothesis- Dexmedetomidine infusion before induction will attenuate haemodynamic response to tracheal intubation better than magnesium sulphate infusion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 156
ASA grade I & II patients with mallampatti grades I & II.
1)Allergy to study medication 2)Difficult airway or Intubation time more than 20 seconds or more than one attempt 3)Hypertensive,Cardiac,Hepatic,Renal,Endocrine,Psychiatric disease & Morbid obesity 4) Pregnant & Nursing women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of infusion Dexmedetomidine with magnesium sulphate on haemodynamic parameters (HR & BP) during endotracheal intubation in adult patients At the time of intubation
- Secondary Outcome Measures
Name Time Method To study the effect of dexmedetomidine & magnesium sulphate on: 1)Sedation
Trial Locations
- Locations (1)
Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi
🇮🇳Delhi, DELHI, India
Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi🇮🇳Delhi, DELHI, IndiaDr Nikita ChoudharyPrincipal investigator9891122144choudhary.20nikita@gmail.com