Biofilm In ear discharge And Role Of Acetic Acid Vs Ciprofloxacin In Its Reductio
- Conditions
- Health Condition 1: H661- Chronic tubotympanic suppurative otitis media
- Registration Number
- CTRI/2021/12/038387
- Lead Sponsor
- Maulana Azad Medical College and associated Lok Nayak Hospitals
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients between 18 to 65 years of age
2.Patients presenting with active chronic otitis media
3.Patients who are not on topical antibiotics treatment for 48 hours or more before sample collection.
4.Patients who are not on systemic antibiotics treatment for a minimum of 7 days before sample collection.
1.Patients suffering from COM who are on systemic antibiotics in the past 7 days of presentation.
2.Patient suffering from squamosal type of chronic otitis media.
3.Patients having ear discharge due to otitis externa or traumatic or neoplastic condition.
4.Known diabetics, immunocompromised patients, or patients with Acute debilitating conditions.
5.Patients with evident fungal or mixed infection (bacterial with fungal)
6.Acute chronic otitis media with complications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the prevalence of biofilm in active mucosal chronic otitis media cases in patients presenting in ENT OPD. <br/ ><br>2.To assess the spectrum and antibiogram of bacteria in active mucosal chronic otitis media cases. <br/ ><br>Timepoint: 3 weeks
- Secondary Outcome Measures
Name Time Method 1.To assess the clinical response to acetic acid and compare it with ciprofloxacin in active mucosal chronic otitis media cases. <br/ ><br>2.To determine correlation between clinical response and in vitro response to ciprofloxacin and acetic acid ear drops in active mucosal chronic otitis media cases. <br/ ><br>Timepoint: 3 weeks