Effects of Smoking State on Decision Making

Not Applicable

Completed

• Conditions: Behavior
• Interventions: Other: smoking abstinence; Other: smoking satiety

• Registration Number: NCT04826276
• Lead Sponsor: Wake Forest University Health Sciences

Brief Summary

Adult smokers will be tested using behavioral and neuroimaging measures after smoking as usual and after overnight abstinence.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2021-03-26
• Study First Submitted QC: 2021-03-29
• Study First Posted: 2021-04-01
• Status Verified: 2022-09
• Study Start: 2022-09-01
• Primary Completion: 2023-03-28
• Study Completion: 2023-03-28
• Last Update Submitted: 2023-06-01
• Last Update Posted: 2023-06-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

• Aged 18-55 years
• Smokes cigarettes or e-cigarettes
• Negative urine drug screen

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Exclusion Criteria

• Unstable or serious medical or mental health condition
• History of serious head trauma
• Pregnancy
• Unsuitable for MRI
• Weight > 350 pounds (maximum allowed for MRI)

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
All Subjects	smoking abstinence	for the abstinence intervention, 12+ hours after smoking will be assessed before assessments following smoking as normal For the satiated intervention, smoking as normal will be assessed first before assessments following 12+ hours of abstinence from smoking
All Subjects	smoking satiety	for the abstinence intervention, 12+ hours after smoking will be assessed before assessments following smoking as normal For the satiated intervention, smoking as normal will be assessed first before assessments following 12+ hours of abstinence from smoking

Primary Outcome Measures

Name	Time	Method
Distress tolerance behavior	through study completion, an average of 1 year	duration on measures of distress tolerance
Effort based decision making	through study completion, an average of 1 year	number of high effort selections

Trial Locations

Locations (1)

Wake Forest University School of Medicine; 🇺🇸 Winston-Salem, North Carolina, United States