The effect of bariatric surgery on pharmacotherapy of psychotropic drugs
- Conditions
- bariatric surgeryantidepressivsantipsychoticsdosage
- Registration Number
- NL-OMON29532
- Lead Sponsor
- St Antonius hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded from participation in this study:
- Known allergy for the administered medicine;
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main study endpoint is the change in drug concentrations in plasma (therapeutic drug monitoring) (mg/L) of the psychotropic drug after bariatric surgery (at 1, 3, 6 and 12 months) compared to the drug concentrations in plasma (therapeutic drug monitoring) before bariatric surgery corrected by the dosage.
- Secondary Outcome Measures
Name Time Method Secondary endpoint is:<br /><br>-the change in mental status, evaluated by the Brief Symptom Inventory (BSI)- questionnaire, after bariatric surgery (at 1, 3, 6 and 12 months), compared to before bariatric surgery <br>