Processing Integration in Neurological Patients Using fMRI

Not yet recruiting

• Conditions: Stroke; Anosognosia; Acute Inflammatory Demyelinating Polyradiculoneuropathy; Neuropsychiatric Conditions; Central and Peripheral Neurodegenerative Pathologies
• Interventions: Device: 3 Tesla Siemens Skyra MRI scanner

• Registration Number: NCT02722070
• Lead Sponsor: Hadassah Medical Organization

Brief Summary

The main objective of the study is to explore and map brain areas involved in processing and perception in patients suffering from neurological pathologies and condition. The investigators hypothesize for example, that a change (compare to healthy subjects) in the perceptual maps and body representation could be detected and characterize in patients suffering from impairments of peripheral nerve conduction.

Detailed Description

Not available

Study Timeline

• Status Verified: 2016-01
• Study Start: 2016-03
• Study First Submitted: 2016-03-23
• Study First Submitted QC: 2016-03-28
• Last Update Submitted: 2016-03-28
• Study First Posted: 2016-03-29
• Last Update Posted: 2016-03-29
• Primary Completion: 2020-03
• Study Completion: 2025-03

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• diagnosis of the investigated neuronal disease

Exclusion Criteria

• contraindication for MRI scan
• pregnancy
• refusal to participate in the study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Healthy Controls	3 Tesla Siemens Skyra MRI scanner	Age matched control for the various clinical groups
Neuropsychiatric patients	3 Tesla Siemens Skyra MRI scanner	-
Neurodegenerative patients	3 Tesla Siemens Skyra MRI scanner	-
Stroke patients	3 Tesla Siemens Skyra MRI scanner	-

Primary Outcome Measures

Name	Time	Method
Hemodynamic responses by measurement of the Blood-oxygen-level dependence(BOLD) signal	2 years	Distinct maps of sensory and multisensory representations related to certain disorders will be sassed by measurement of the Blood-oxygen-level dependence(BOLD) signal.