Neurofunctional and Neurochemical Markers of Treatment Response in Bipolar Disorder

Phase 4

• Conditions: Bipolar I Disorder
• Interventions: Drug: Lithium

• Registration Number: NCT00608075
• Lead Sponsor: University of Cincinnati

Brief Summary

The purpose of the research is to study brain structure, function and chemistry of patients with bipolar disorder who are receiving lithium, an FDA-approved treatment for bipolar mania, in order to better understand who benefits from treatment and why they respond to medications. Studying this may help improve treatment and outcome in patients with bipolar disorder.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-04
• Study First Submitted: 2008-01-23
• Study First Submitted QC: 2008-01-23
• Study First Posted: 2008-02-06
• Primary Completion: 2015-07
• Status Verified: 2016-10
• Last Update Submitted: 2016-10-05
• Last Update Posted: 2016-10-06
• Study Completion: 2017-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 260

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
1	Lithium	Manic Patients
2	Lithium	Depressed Patients

Primary Outcome Measures

Name	Time	Method
The purpose of the research is to study brain structure, function and chemistry of patients with bipolar disorder who are receiving lithium.	8 weeks

Trial Locations

Locations (1)

University of Cincinnati; 🇺🇸 Cincinnati, Ohio, United States