Longitudinal Multimodal Neuroimaging Studies in Patients With First Episode Psychosis

Completed

• Conditions: Psychotic Disorders
• Interventions: Other: Observational

• Registration Number: NCT01688765
• Lead Sponsor: Mclean Hospital

Brief Summary

The purpose of this study is to investigate the structural, functional and chemical brain abnormalities in patients with first episode psychosis and assess the evolution of these abnormalities during the course of the disease.

Detailed Description

The purpose of this study is to investigate the structural, functional and chemical brain abnormalities in patients with first episode psychosis and assess the evolution of these abnormalities during the course of the disease.

The study design is case-control, there are no interventions.

Study Timeline

• Study First Submitted: 2012-09-17
• Study First Submitted QC: 2012-09-17
• Study First Posted: 2012-09-20
• Study Start: 2012-10-17
• Status Verified: 2022-09
• Primary Completion: 2022-09-23
• Study Completion: 2022-09-23
• Last Update Submitted: 2022-09-24
• Last Update Posted: 2022-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 187

Inclusion Criteria

• Clinical diagnosis of first episode of a psychotic disorder
• Healthy controls with no psychiatric disorder history

Exclusion Criteria

• Significant neurological or medical illness history
• Ages <18 or >45

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
First Episode Psychosis Patients	Observational	Individuals experiencing a first episode of psychosis
Healthy Controls	Observational	Psychiatrically healthy individuals

Trial Locations

Locations (1)

McLean Hospital; 🇺🇸 Belmont, Massachusetts, United States