PAtient Treatment Analysis: Hospital and Wide-ranging Out-of-hospital Care Assessment Yields Insights Into Heart Failure Outcomes

Recruiting

• Conditions: Heart Failure

• Registration Number: NCT06338878
• Lead Sponsor: Pr. Nicolas GIRERD

Brief Summary

This is a monocentric cohort study conducted in the cardiology department of Nancy hospital. The main purpose of the study is to document the global management strategy of patients hospitalized for heart failure and evaluate the association between patient's care and post-hospitalization outcome.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-02
• Study First Submitted: 2024-02-23
• Study Start: 2024-03-01
• Study First Submitted QC: 2024-03-27
• Last Update Submitted: 2024-03-27
• Study First Posted: 2024-04-01
• Last Update Posted: 2024-04-01
• Primary Completion: 2027-01
• Study Completion: 2029-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Man or women ≥ 18 years
• Patients hospitalized for cardiac decompensation (ESC 2016 and 2021 criteria)

Exclusion Criteria

• Patient expressing refusal to participate in research
• Patient who is a minor or under administrative protection
• Pregnant women
• Patient with ventricular assistance
• Patient with congenital heart disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-cause post-hospitalization mortality	Within 1 year following hospital discharge	Composite endpoint of all-cause post-hospitalization mortality and rehospitalization for heart failure with outcome 2
Rehospitalization for heart failure	Within 1 year following hospital discharge	Composite endpoint of all-cause post-hospitalization mortality and rehospitalization for heart failure with outcome 1

Secondary Outcome Measures

Name	Time	Method
Evolution of renal function	During hospitalization for up to 2 months and within 1 year after discharge.	Note: assessed by creatinine levels and GFR by CKD EPI
Influenza and pneumococcal vaccination status	Within 1 year following hospital discharge
All-cause Rehospitalization	Within 1 year following hospital discharge	Assessed by: Rehospitalization for any cause other than hear failure after discharge.
Percentage of maximum dose of each cardiotropic treatment indicated in heart failure according to ESC recommendations	Within 1 year following hospital discharge
All-cause mortality	Within 1 year following hospital discharge

Trial Locations

Locations (1)

CHRU de Nancy; 🇫🇷 Nancy, France