Multiple sclerosis lesion characterization on ultra-high-field MRI: Comparative pilot study of 9.4 vs 7 vs 3 tesla

Completed

• Conditions: 10012303; MS; multiple sclerosis

• Registration Number: NL-OMON52035
• Lead Sponsor: Zuyderland Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 8 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Relapsing remitting MS patients (according to the 2017
McDonald criteria) between age 18-65 years, who had a new brain MRI lesion in
the past 15 months. Choosing an upper limit of 65 years, limits the age-related
vascular white matter lesion burden on the brain scans.

Exclusion Criteria

Patients who are unable to undergo MRI investigations due to (i) non-compatible
implanted material/devices or (ii) due to not being able to lie flat long
enough because of another medical condition, will be excluded.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Difference in white matter lesion volume/count, cortical lesion volume/count,<br /><br>percentage of lesions with central veins, tolerability of the investigation,<br /><br>between the field strengths, quantitative image quality parameters (signal- and<br /><br>contrast-to- noise ratios).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>.</p><br>