Assessment of gastroesophageal reflux in patients without reflux symptoms
Not Applicable
Recruiting
- Conditions
- Gastroesophageal reflux disease
- Registration Number
- JPRN-UMIN000043956
- Lead Sponsor
- Tohoku University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 23
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Taking NSAIDs, steroids, immunosuppresive medications (2) Prior abdominal surgery (3) Prior chemotherapy (4) Diabetes and collagen disease (5) Taking acid suppressive medications and prokinetics (6) Prior allergic reaction to Xylocain (7) Difficulty in inserting a catheter due to narrow nasal cavity
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Esophageal acid exposure in MII-pH
- Secondary Outcome Measures
Name Time Method 1. Total reflux episodes including acid and non-acid in MII-pH 2. Total supragastric belching (SGB) episodes in MII-pH 3. Transient lower esophageal sphincter relaxation (TLESR) episodes in a postprandial period in HRIM 4. TLESR with reflux episodes in a postprandial period in HRIM 5. Postprandial SGB episodes in MII-pH 6. Postprandial rumination episodes in HRIM