Effect of methylprednisolone when compared to oral prednisolone in treatment of children with West syndrome
Not Applicable
- Conditions
- Health Condition 1: null- West syndrome
- Registration Number
- CTRI/2017/12/010877
- Lead Sponsor
- Sanjiv Nanda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Newly diagnosed patients aged 2 â?? 30 months with epileptic spasms in clusters with electroencephalographic evidence of hypsarrhythmia or its variants with or without
developmental delay
Exclusion Criteria
1.Children with recognized progressive neurological illness will be excluded.
2.Children with renal, pulmonary, cardiac or hepatic dysfunction
3.Severe malnutrition ( weight for length and height for less than 3 SD for mean as per WHO growth charts )
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of children with cessation of spasmTimepoint: 4 weeks
- Secondary Outcome Measures
Name Time Method Proportion of children with Fifty percentage reduction in frequency of spasmTimepoint: 4 weeks;Proportion of children with ninty percentage reduction in frequency of spasmTimepoint: 4 weeks;Proportion of children with resolution of HypsarrhythmiaTimepoint: 4 weeks;Safety of intervention in terms of nature and proportion of the adverse effectsTimepoint: 4 weeks