Research on acute interstitial nephritis disease
- Conditions
- Acute interstitial nephritis
- Registration Number
- SLCTR/2014/007
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Terminated
- Sex
- Not specified
- Target Recruitment
- 200
1.Two or more elevated (value more than upper limit of the normal) serum creatinine values done within 3 days and
2.Normal size kidneys defined as more than 9 cm longitudinal diameter and normal anatomy on ultrasound scan
3. Age less than 60 years
1.History of chronic kidney disease, diabetes mellitus, chronic hypertension, connective tissue diseases, vacuities,hyperuricemia, pyelonephritis, renal stone disease and any obstructive uropathy, polycystic kidney disease or any other known genetic disease, glomerular nephritides, snake bite, and childhood renal disease.
2.Whose current abnormal creatinine is explainable by recent exposure to nephrotoxic drugs (non-steroidal anti-inflammatory drugs, gentamicin…etc.) or toxins.
3.BP >160/100mmhg untreated or >140/90 on up to two antihypertensives
4.Two or more fasting blood sugar more than 7 mmol/l
5.UFR showing red blood cells more 50 per HPF with more than 80% dysmorphic cells or nephrotic range proteinuria or pus cells more than 100 per HPF with a positive urine culture
6.Ultrasound scan revealing unilateral renal involvement
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum creatinine [2 weeks, one month, six month, two years]<br>
- Secondary Outcome Measures
Name Time Method 1.Reaching stage 4 kidney disease <br>2.Death <br>3.Small contracted kidneys<br> [6months, 2 years]<br>