Zishen Yutai Pill and aspirin in the prevention of preeclampsia: a ramdomized control trial
- Conditions
- Preeclampsia
- Registration Number
- ITMCTR2000004020
- Lead Sponsor
- Shenzhen Luohu People's Hospital (The Third Affiliated Hospital of Shenzhen University)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- Not specified
1. Singleton pregnancy;
2. Subjects who are 12-20 weeks pregnant;
3. The subjects who signed the informed consent form for clinical research;
4. High risk population of preeclampsia.
Evaluation index:
Has one or more of the following risk factors:
History of preeclampsia;
diabetes;
Chronic hypertension;
Chronic kidney disease;
SLE or antiphospholipid antibody syndrome.
Or with the following > = 2 risk factors:
Primipara;
BMI > 30kg / m2 before pregnancy,;
The age of pregnant women was 35 years old;
More than 10 years from the last pregnancy;
The mother or sister had a history of preeclampsia;
Previous pregnancies were smaller than gestational age infants;
History of placental abruption;
Family history of hypertension.
1. Patients allergic to aspirin or Zishenyutai pills;
2. Fetal malformation or chromosomal abnormality;
3. Patients with liver and kidney dysfunction or heart disease;
4. Subjects who have suffered from bleeding diseases such as gastric ulcer;
5. Mental patients;
6. Alcoholics or drug addicts;
7. Subjects who do not plan to have regular prenatal examination and delivery in the research unit.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence of preeclampsia;
- Secondary Outcome Measures
Name Time Method incidence of preeclampsia that appear before 34 weeks of pregnancy;incidence of pregnancy hypertention;incidence of preterm birth;incidence of severe preeclampsia;