To assess the effect ofSanshodhanKarma i.e. Vaman and Virechan on lipid profile.

Phase 2

Not yet recruiting

• Conditions: 300 relatively healthy individuals of either sex

• Registration Number: CTRI/2021/04/033039
• Lead Sponsor: National Institute of Ayurveda

Brief Summary

300 relatively healthy individuals of either sex will be randomly divided in to two equal groups namely group A and group B Group A individuals will undergo Vaman Karma and group B individuals will undergo Virechan karma. Blood samples for lipid profile will be collected for each individual. On the day before paachan karma, on the day before commencement of Snehapaan, Next day of completion of snehapaan and after completion of SansarjanKrama and followup 15 days after sansarjan karma.In both groups Paachan with panchakolchurna 3gm for 7 days snehapaan with cow ghee in increasing dosage starting dose with 50ml and 25ml dose will be increased daily till the achievement of Samyaksnehalakshana. In group A Vaman will be done with Aakanthapaan of milk, Vamak yoga will be Madanfalpippalichurna 3gm, Kutajbeej churna 2gm, Patola patra 2gm madhu 10ml and saindhav 2gms, Madhuyashti faant with adequate quantity will be used as Vamanopag drug. In group B Triphala, Trivrit, Danti kwath 200ml will be given for Virechan. Total expected duration of completion of this research trial will be approximately 3years.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-04-22
• Study Start: 2021-04-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Male or Female Subjects in the age group of 18 to 60 years, both inclusive.
• Subjects who are willing to undergo sanshodhan karma.
• Subjects of female gender or non-pregnant, non-lactating females.
• A urine pregnancy test is required for all female subjects of childbearing potential unless subject has had a hysterectomy, tubal ligation, or is > 2 years postmenopausal.
• Subjects willing to follow the procedures as per the study protocol and voluntarily sign an informed consent form.

Exclusion Criteria

• Subjects with any known systemic disease.
• Known cases of Severe/Chronic hepatic or renal disease.
• Known case of any active malignancy.
• Subjects giving history of significant cardiovascular event.
• Subjects having known chronic, contagious infectious disease, such as active tuberculosis, Hepatitis B or C, or HIV.
• Pregnant and Lactating females.
• Those who are contraindicated for sanshodhan karma.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
to evaluate changes in lipid levels after Ghritapan and Sanshodhan Karma.	Blood samples for lipid profile will be collected for each individual. On the day before paachan | karma, on the day before commencement of Snehapaan, Next day of completion of snehapaan | and after completion of SansarjanKrama and followup 15 days after sansarjan karma.

Secondary Outcome Measures

Name	Time	Method
To assess the probable risk factors of Ghritapan and Sanshodhankarma on the basis of lipid	levels

Trial Locations

Locations (1)

National Institute of Ayurveda; 🇮🇳 Jaipur, RAJASTHAN, India

National Institute of Ayurveda

🇮🇳Jaipur, RAJASTHAN, India

Dr Gopesh Mangal

Principal investigator

8619849011

gmangal108@gmail.com