A comparative clinical study to assess the effect ofSanshodhanKarma i.e. Vaman and Virechan on lipid profile.
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- to evaluate changes in lipid levels after Ghritapan and Sanshodhan Karma.
研究概览
简要总结
300 relatively healthy individuals of either sex will be randomly divided in to two equal groups namely group A and group B Group A individuals will undergo Vaman Karma and group B individuals will undergo Virechan karma. Blood samples for lipid profile will be collected for each individual. On the day before paachan karma, on the day before commencement of Snehapaan, Next day of completion of snehapaan and after completion of SansarjanKrama and followup 15 days after sansarjan karma.In both groups Paachan with panchakolchurna 3gm for 7 days snehapaan with cow ghee in increasing dosage starting dose with 50ml and 25ml dose will be increased daily till the achievement of Samyaksnehalakshana. In group A Vaman will be done with Aakanthapaan of milk, Vamak yoga will be Madanfalpippalichurna 3gm, Kutajbeej churna 2gm, Patola patra 2gm madhu 10ml and saindhav 2gms, Madhuyashti faant with adequate quantity will be used as Vamanopag drug. In group B Triphala, Trivrit, Danti kwath 200ml will be given for Virechan. Total expected duration of completion of this research trial will be approximately 3years.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Male or Female Subjects in the age group of 18 to 60 years, both inclusive.
- •Subjects who are willing to undergo sanshodhan karma.
- •Subjects of female gender or non-pregnant, non-lactating females.
- •A urine pregnancy test is required for all female subjects of childbearing potential unless subject has had a hysterectomy, tubal ligation, or is > 2 years postmenopausal.
- •Subjects willing to follow the procedures as per the study protocol and voluntarily sign an informed consent form.
排除标准
- •Subjects with any known systemic disease.
- •Known cases of Severe/Chronic hepatic or renal disease.
- •Known case of any active malignancy.
- •Subjects giving history of significant cardiovascular event.
- •Subjects having known chronic, contagious infectious disease, such as active tuberculosis, Hepatitis B or C, or HIV.
- •Pregnant and Lactating females.
- •Those who are contraindicated for sanshodhan karma.
结局指标
主要结局
to evaluate changes in lipid levels after Ghritapan and Sanshodhan Karma.
时间窗: Blood samples for lipid profile will be collected for each individual. On the day before paachan | karma, on the day before commencement of Snehapaan, Next day of completion of snehapaan | and after completion of SansarjanKrama and followup 15 days after sansarjan karma.
次要结局
- To assess the probable risk factors of Ghritapan and Sanshodhankarma on the basis of lipid(levels)