Comparison of effects of oral melatonin and alprazolam as preoperative medicine and their effects on post operative recovery in patients undergoing ear surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/08/044912
- Lead Sponsor
- Sharda Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patient undergoing tympanoplasty surgeries under general anaesthesia
2. ASA class I and II
Exclusion Criteria
1. Patient refusal to participate in the study
2. Patients receiving steroids, analgesics, antiemetic, sedatives and antipsychotics.
3. Patients having history of endocrine, cardiovascular, renal or CNS disease.
4. Patients allergic to study drugs.
5. BMI > 30 kg m-2
6. Patient having chronic pain and any mental illness
7. Pregnant patients
8. Patients with inability to read and write basic alphabets and numbers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effects of melatonin and alprazolam on preoperative anxiety.Timepoint: 2 hours post surgery
- Secondary Outcome Measures
Name Time Method 1. To compare the effects of melatonin and alprazolam on: <br/ ><br>(a) Pre-operative sedation <br/ ><br>(b) Pre-operative cognition <br/ ><br>2. To compare the effects of melatonin and alprazolam on: <br/ ><br>(a) Post-operative sedation <br/ ><br>(b) Post-operative anxiety <br/ ><br>(c) Post-operative cognition <br/ ><br>3. To compare post operative pain in the two groupsTimepoint: 2 hours post surgery