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Testing New Method of Analyzing MR Images

Phase 1
Terminated
Conditions
Breast Abnormalities
Registration Number
NCT00630318
Lead Sponsor
Indiana University
Brief Summary

Preliminary imaging study to test for future use of this MRI-imaging for evaluating anti-angiogenesis treatment.

Detailed Description

The purpose of this study is to develop and evaluate new MR imaging techniques and protocols for non-invasive monitoring of anti-angiogenesis treatment of breast cancer. This feasibility study is a preliminary imaging study to test this imaging protocol on subjects already undergoing MR for clinical purposes.

The specific objective of this research study is to develop and validate both MRI and functional MRI data acquisition methods, task paradigms, and post-processing techniques to ensure reliability of results.

The information derived from this research is intended to be applied to a future study of subjects undergoing experimental anti-angiogenesis drug therapy.

Recruitment & Eligibility

Status
TERMINATED
Sex
Female
Target Recruitment
12
Inclusion Criteria
  • Females
  • Age 18 years or greater
  • Undergoing breast MRI exam
Exclusion Criteria
  • Pregnancy
  • Contraindication for MRI on standard screening checklist for clinically indicated examinations (i.e. metal devices/implants; history of claustrophobia)
  • History/presence of any of the following to the breast: injury; breast implant; surgical or interventional procedure; clinically significant abnormality

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
To provide preliminary data for a larger study that this type of imaging can be used to monitor the effectiveness of anti-angiogenic therapy.After analysis of images
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Methodist Hospital

🇺🇸

Indianapolis, Indiana, United States

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