To compare the effect of spinal anaesthesia and general anaesthesia on blood glucose levels in lower abdominal surgeries

Phase 4

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2024/05/068062

Lead Sponsor: Department of Anaesthesiology

Brief Summary: The Etiology of hyperglycemia is multifactorial , but is thought primarily to be the result of activation of the sympathoadrenal system ,with contributions from the hypothalamus and adenohypophysis. The stress response triggers an increase in levels of plasma catecholamines and glucocorticoids ,which in turn lead to hyperglycemia . cortisol also has a huge impact on the glucose metabolism in stress, because by increasing glycogenolysis and glucogenesis it can lead to hyperglycemia . the aim of the study is t determine the significance of spinal anaesthesia in supressing the metabolic , and hemodynamic response to surgical stress during and after elective abdominal urological and orthopaedics surgery compared with the technique of general anaesthesia

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 70

Inclusion Criteria

1.Patients undergoing scheduled elective surgeries 2.patients willing to give informed written consent 3.ASA Grade 1 and 2.

Exclusion Criteria

1.Any Cardiovascular disorder 2.Any Respiratory Disorder 3.diabetic patients 4.Hypertensive patients 5.Neurological disorders 6.Drug allergy , if any.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean Blood Glucose Concenteration	5 minutes before induction \| 5 minutes after induction \| 5 minutes before completion \| 30 minutes after completion

Secondary Outcome Measures

Name	Time	Method
Mean Hemodynamic variables	Baseline

Trial Locations

Locations (2): SMS Medical college
🇮🇳
Jaipur, RAJASTHAN, India
SMS Medical college and attached hospitals
🇮🇳
Jaipur, RAJASTHAN, India
SMS Medical college
🇮🇳Jaipur, RAJASTHAN, India
Dr Sagar
Principal investigator
8107191195
sagardhamija.dhamija@gmail.com