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Efficacy of desidustat in erythropoietin hyporesponsiveness among CKD patients

Phase 4
Conditions
Health Condition 1: N186- End stage renal disease
Registration Number
CTRI/2024/05/066867
Lead Sponsor
Arivazhagan S
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

ESRD patients on maintenance hemodialysis with anemia (hemoglobin level below 8g/dl) and receiving erythropoietin alpha and iron injection.

Exclusion Criteria

Patient with red blood cell transfusion (within 4 weeks)

History of renal transplantation

Previous or concurrent cancer

Pregnancy and lactation

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Improvement in the hemoglobin level in hyporesponsive state <br/ ><br>The adjunct therapy will be better when compared with control treatment <br/ ><br>Can able to assess the safety of the treatmentTimepoint: Hemoglobin <br/ ><br>Hematocrit <br/ ><br>The hemoglobin and hematocrit value follow up to the baseline, after 4th week, 8th week and 12th week
Secondary Outcome Measures
NameTimeMethod
To reduce the number of hospital staysTimepoint: Number of hospital stay <br/ ><br>The hospital stay outcome calculated based on admission & discharge of patient (inpatient hospital days). in that days between the admission & discharge are used to identify the hospital stays
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