Vestibular Socket Therapy in Immediate Implants With Grafting Materials

Not Applicable

• Conditions: Dental Implant; Tooth Extraction; Extarction Socket
• Interventions: Other: VST with collagen plug soaked in blood; Other: VST with a particulate bone graft composed of two thirds autogenous cortical chips harvested from the surgical site and one third of bovine deprotinzed particles; Other: VST with Allograft Demineralized bone matrix Grafton

• Registration Number: NCT04957654
• Lead Sponsor: Mohamed Mofreh Hamada Hamed

Brief Summary

The current research aims at evaluating the outcomes of the vestibular socket therapy in immediate implants using collagen plug, demineralized freeze-dried bone allograft, and deproteinized bovine bone minerals at both radiographic and clinical levels

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-16
• Status Verified: 2021-07
• Study First Submitted: 2021-07-05
• Study First Submitted QC: 2021-07-05
• Last Update Submitted: 2021-07-05
• Study First Posted: 2021-07-12
• Last Update Posted: 2021-07-12
• Primary Completion: 2022-04-30
• Study Completion: 2022-07-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Patients will be included if they have one or more hopeless teeth without signs of acute infection in the maxillary anterior region.
• Remaining roots or non-restorable teeth with sufficient bone apically and palatably to allow proper implant positioning with sufficient primary stability.
• Optimal compliance as evidenced by no missed treatment appointments and a positive attitude towards oral hygiene.
• Medically free

Exclusion Criteria

• Medically compromised patients and systemic conditions precluding implant and periodontal surgery.
• Smokers, diabetics, pregnant or lactating women.
• History of chemotherapy, radiotherapy in head and/or neck region.
• Bisphosphonate therapy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
VST with collagen plug soaked in blood	VST with collagen plug soaked in blood	-
VST with autogenous cortical chips and bovine deprotinzed particles	VST with a particulate bone graft composed of two thirds autogenous cortical chips harvested from the surgical site and one third of bovine deprotinzed particles	-
VST with Allograft Demineralized bone matrix Grafton	VST with Allograft Demineralized bone matrix Grafton	-

Primary Outcome Measures

Name	Time	Method
changes in facial plate height	at baseline, 6 and 12 months	Each group will be subjected to: Cone beam computed tomography (CBCT) at baseline, 6 months, and 12months to assess height of labial (facial) plate of bone and implant survival
changes in facial plate thickness	at baseline, 6 and 12 months	Each group will be subjected to: Cone beam computed tomography (CBCT) at baseline, 6 months, and 12months to assess the thickness of the labial (facial) plate of bone and implant survival

Secondary Outcome Measures

Name	Time	Method
changes in peri-implant mucosal level	at baseline, 3rd and 6th months	Each group will be subjected to Intraoral scanning at baseline, 6 months and 12 months. The changes in peri-implant mucosal level will be assessed by superimposition of scanning files of different intervals to monitor the changes in surface area calculated by software.

Trial Locations

Locations (1)

Faculty of Dentistry, Tanta University; 🇪🇬 Tanta, Egypt