Investigation of the mechanical properties of pathological scars using suction-based Optical Coherence Elastography
Completed
- Conditions
- 1. Scars 2. Cutaneous cicatrication10014982
- Registration Number
- NL-OMON55099
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
* Age: 18 years or older
* Competent
* Keloid or hypertrophic scar.
Exclusion Criteria
* Language barrier
* Immature scar/open wounds
* Connective tissue disorders (e.g. Marfan, Ehlers Danlos, Cutis Laxa)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main objective of this study is to determine whether OCT-based suction<br /><br>elastometry is a proper tool to quantify elasticity of mature keloid and<br /><br>hypertrophic scars and healthy skin in human subjects. </p><br>
- Secondary Outcome Measures
Name Time Method <p>What is the concurrent validity of this device? Do the results correlate with<br /><br>the item *pliability* of the POSAS.<br /><br>Can we use this device for the analysis of pathological scars. Although this<br /><br>device does not differ tremendously from the Cutometer, the feasibility needs<br /><br>to be addressed in this pilot. Are the measurements practical and timely? Does<br /><br>a single measurement provide sufficient data for the quantification of the<br /><br>above mentioned parameters?<br /><br>Can this device be used to measure scar specific differences in epidermal<br /><br>thickness</p><br>