To evaluate the efficacy of pretreatment of vein with plain intravenous lignocaine before propofol with that of premixed solution of lignocaine and propofol to decrease pain on injection during propofol induction of anaesthesia:
Not Applicable
- Conditions
- Health Condition 1: I999- Unspecified disorder of circulatory system
- Registration Number
- CTRI/2024/04/065103
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients who need propofol as induction anaesthetic agent in providing general anaesthesia for the surgery
Patients between age 18-65 Years of either sex.
Patients belongs to American Society of Anaesthesiologists (ASA) physical status classification system grades of I, II & III [45](Annexure – 3)
will be included into the study.
Exclusion Criteria
Unwilling participants.
Patients belongs to ASA grade more than three.
Patients with hemodynamic instability precluding the use of propofol.
Patients with a history of Hypersensitivity to study drugs.
Patients who are Allergy to eggs and soya.
Patients with poor venous access .
Pregnant and lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the intensity of pain during propofol induction.Timepoint: 0 minute, 1 minute , 2minute, 3minute
- Secondary Outcome Measures
Name Time Method To compare the haemodynamic changes associated with the interventions upon propofol administration (Heart rate - HR, Systolic Blood Pressure - SBP, Diastolic Blood Pressure - DBP and Mean Arterial Pressure - MAP). <br/ ><br> <br/ ><br>Adverse events: Allergic reactions (chills & rigors, urticarial rashes, itching, swelling at the site of injection), arrhythmias during the study period and incidence of severe thrombophlebitis (tenderness and erythema) within 24 hours will also be observed. <br/ ><br> <br/ ><br>Timepoint: 0 minute, 1 minute , 2minute, 3minute and 24hrs