Effect evaluation and related mechanism research on different stages of IgA nephropathy treated by supplementing Qi, nourishing Yin and removing blood stasis
- Conditions
- IgA
- Registration Number
- ITMCTR2100004291
- Lead Sponsor
- Zhejiang Provincal Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. In line with Western medicine IgA nephropathy and renal function in line with the diagnostic criteria of CKD stage 1-4;
2. It conforms to the diagnostic criteria of TCM syndrome differentiation;
3. Patients are between 18 and 75 years of age, regardless of gender;
4. Infection, acidosis, electrolyte disturbance and hypertension have been well controlled;
5. No other organ function failure;
6. Have good compliance, have not participated in other clinical trials in recent half a year;
7. Informed and willing to accept clinical investigators.
1. People who are allergic or allergic to known ingredients of the study drug;
2. Patients diagnosed with acute renal failure, and patients undergoing hemodialysis or peritoneal dialysis;
3. Patients with serious damage to the heart, liver, lung and other organs, or patients with wasting diseases such as malignant tumor or active tuberculosis;
4. Patients with gastrointestinal bleeding, or need to take other types of Chinese medicine during the test;
5. Those who do not cooperate with treatment;
6. Recent history of surgery;
7. Pregnant and lactating women;
8. Participants considered inappropriate by the investigator to participate in clinical trials.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ang(1-7);ACE II;24-hour urinary protein quantity;Anti-NADPH oxidase 4;AOPPs;ACE;Glutathione peroxidase;ACE2;MDA;
- Secondary Outcome Measures
Name Time Method