The safety and efficacy of repetitive transcranial magnetic stimulation on eating behaviors and body weight in obesity: A randomized, single-center, single blinded, parallel design, placebo-controlled study
- Conditions
- Endocrine, nutritional and metabolic disease
- Registration Number
- KCT0002548
- Lead Sponsor
- The Catholic University of Korea, St. Vincent's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
• 19 to 70 years old
• BMI = 25kg/m2
• Ability to write, read, and understand all elements of the study
• Informed consent signed.
• Past history of head or eye injury or epilepsy
• Body metallic implants, pacemaker, claustrophobia and any other contraindication to fMRI or rTMS;
• Current use of psychotropic drugs (except for antidepressants on a stable dose for at least one month)
• Current use of any anti-obesity drug (three months washout period for any other medication)
• Pregnancy or breast feeding
• Past history of Diabetes Mellitus, thyroid disease, renal disease and malignancy
• Major psychiatric disorder requiring immediate treatment
• Substance dependence
• Individuals currently receiving any psychological therapy for their eating disorder
• Substance dependence
• severe infection, metabollic acidosis, acromegaly adn Cushing syndrome
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in Body Weight
- Secondary Outcome Measures
Name Time Method Korean eating attitude test (KEAT-26) scores;HOMA-IR;visceral fat assessed by CT;structural and functionl change assessed by brain MRI;CERAD-K score