Effects of high dose angiotensin II receptor blocker or combination of angiotensin II and calcium channel blocker on ambultory blood pressure in patients with hypertension and type 2 diabetes (randomized controlled clinical trial)
Not Applicable
Recruiting
- Conditions
- Hypertension with type 2 diabetes mellitus
- Registration Number
- JPRN-UMIN000020632
- Lead Sponsor
- Department of General Internal Medicine, Kyushu University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 110
Inclusion Criteria
Not provided
Exclusion Criteria
(1) secondary hypertension (2) past histody of cardiovascular disease (3) resistant hypertension (4) inadequacy for this therapy (5) severe renal dysfunction (eGFR < 45 mL/min/1.73m2) (6) severe liver dysfunction (Child-Pugh: class B or C) (7) having malignancy or collagen disease (8) chronic Af (9) pregnancy or lactation in women (10) history of allergy for olmesartan medoxomil or azelnidipine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change in ambulatory blood pressure (nighttime SBP) between baseline and after 12 weeks of treatment
- Secondary Outcome Measures
Name Time Method