Dermatological Abnormalities in Beta-thalassemia Major

• Conditions: Beta-Thalassemia

• Registration Number: NCT03894605
• Lead Sponsor: Assiut University

Brief Summary

to study the frequency and pattern of dermatological abnormalities in egyptian childern with beta thalassemia.relationof abnormalities to duration of disease and frequency of transfusion

Detailed Description

thalassemia refers to agroup of inherited disease characterized by decreased or absent synthesis of normal globin .skinvdisorders are usually neglected and frequently underdiagnosed among these patients.skin disease specially pruritus and xerosis are observed highly frequently in patients with beta-thalassemia.pityriasis alba is arelatively common skin disorder.the trophic skin changes and leg ulcers occurred after the age of 15 years

Study Timeline

• Status Verified: 2019-03
• Study First Submitted: 2019-03-22
• Study First Submitted QC: 2019-03-27
• Last Update Submitted: 2019-03-27
• Study First Posted: 2019-03-28
• Last Update Posted: 2019-03-28
• Study Start: 2020-03-02
• Primary Completion: 2021-03-02
• Study Completion: 2021-04-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 125

Inclusion Criteria

Not provided

Exclusion Criteria

• patient with other hemolytic anemia. childern with any abnormalities prior to the diagnosis of thalassemi

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The percentage of patients with dermatological disorders due to iron overload Iron overload cause dermatological abnormalities	one month	the number of patients who develop any dermatological disorder as a result of iron overload after frequent blood transfusion