Different Metabolic Characteristics in the Presence of Brown Adipose Tissue in Humans

Completed

• Conditions: Metabolic Syndrome

• Registration Number: NCT01430338
• Lead Sponsor: Korea University

Brief Summary

Functional brown adipose tissue (BAT) exists in adult humans and can be detected by PET and especially during acute cold exposure. It is conceivable that BAT activity might reduce the risk of developing obesity since fat stores are used for thermogenesis, and a directed enhancement of adipocyte metabolism might have value in weight reduction. So it is important to know the different metabolic characteristics in human adults who have detected BAT. Therefore, the purpose of the investigators study is to compare different metabolic characteristics in the presence of brown adipose tissue in humans.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-12
• Study First Submitted: 2011-08-24
• Status Verified: 2011-09
• Study First Submitted QC: 2011-09-07
• Study First Posted: 2011-09-08
• Primary Completion: 2011-12
• Last Update Submitted: 2015-03-16
• Last Update Posted: 2015-03-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

• Patients who underwent 18FDG-PET/CT scan year between 2008-2010

Exclusion Criteria

• History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
• Diabetes
• Stage 2 hypertension
• Severe renal or hepatic disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
presence metabolic syndrome	5 months

Secondary Outcome Measures

Name	Time	Method
adipokines	5 months
BMI	5 months
sarcopenia	5 months
visceral fat area	5 months

Trial Locations

Locations (1)

korea University Guro Hospital; 🇰🇷 Seoul, Korea, Republic of