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Clinical Trials/NCT06579872
NCT06579872
Recruiting
N/A

Association Between Cardiopulmonary Function, Mobility, Walking Ability, and Plantar Pressure Changes in Patients With Chronic Obstructive Pulmonary Disease: A Case-Control Study

Fu Jen Catholic University1 site in 1 country60 target enrollmentDecember 12, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Chronic Obstructive Pulmonary Disease
Sponsor
Fu Jen Catholic University
Enrollment
60
Locations
1
Primary Endpoint
plantar pressure
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

It aims to understand the differences in everyday mobility and activity capabilities among patients with varying disease progression and severity, to serve as reference indicators for evaluating the effectiveness of pulmonary rehabilitation exercise training.

Detailed Description

Background: Chronic respiratory diseases and Chronic Obstructive Pulmonary Disease (COPD) are major causes of chronic illness and death worldwide. Patients with chronic respiratory diseases experience muscle weakness and respiratory difficulties, leading to restricted physical activity, decreased functional capacity, exercise intolerance, and limb muscle atrophy. While exercise training can effectively improve limb strength, there is a lack of objective data exploring different disease progressions and clinical cardiopulmonary limitations, hence this study utilizes plantar pressure distribution to research lower limb strength and cardiopulmonary function in patients, hoping to identify relevant indicators for necessary exercise training. Methods: The study plans to enroll 60 participants, divided into two groups (30 in the control group and 30 in the case group) matched 1:1. The study will be conducted at the pulmonary rehabilitation therapy room on the sixth floor of Fu-Jen Catholic University Hospital. In addition to basic demographic and clinical physiological parameters, all participants will undergo the 6-minute walk test, the timed up and go test, simple pulmonary function tests, body composition analysis, and statistical analysis. Effect: The trial is expected to effectively determine which patients require exercise training based on the correlation between plantar pressure analysis and results from the 6-minute walk test and timed up and go test. These results are anticipated to correlate positively with disease severity.

Registry
clinicaltrials.gov
Start Date
December 12, 2024
End Date
December 31, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ke-Yun, Chao

Group leader of Respiratory Therapists

Fu Jen Catholic University

Eligibility Criteria

Inclusion Criteria

  • Age between 45 and 65 years
  • Patients with chronic respiratory diseases requiring pulmonary rehabilitation
  • Signed informed consent form

Exclusion Criteria

  • Current tracheostomy
  • Home use of oxygen therapy or ventilators
  • Diagnosed with severe left heart failure (NYHA III-IV)
  • Patients diagnosed with neuromuscular diseases
  • Had an acute exacerbation of COPD in the past three months
  • Unable to perform cardiopulmonary exercise testing

Outcomes

Primary Outcomes

plantar pressure

Time Frame: 20 minutes

The correlation between foot pressure indices and functional tests

Secondary Outcomes

  • self-feedback questionnaires(20 minutes)
  • cardiopulmonary function(20 minutes)

Study Sites (1)

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