Comparison of addition of a sedative drug Dexmedetomidine in Local Anaesthetic drug Ropivacaine 0.1% concentration mixture with plain Ropivacaine in regional Nerve block given for pain relief after Knee Replacement surgery
Not Applicable
- Conditions
- Health Condition 1: - Health Condition 2: M179- Osteoarthritis of knee, unspecifiedHealth Condition 3: M171- Unilateral primary osteoarthritisof knee
- Registration Number
- CTRI/2023/02/049732
- Lead Sponsor
- SIR H N RELIANCE FOUNDATION HOSPITAL AND RESEARCH CENTRE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA grade 1,2,3 scheduled for unilateral total knee replacement under spinal anesthesia
BMI 20-30kg/m2
Exclusion Criteria
allergic to any study drugs
pregnant patients
patients in whom nerve block could not be performed as per methodology
patients on pre operative oral opioids
patients and or relatives not willing for procedure
ASA grade 4 ,age <18 and >80yrs
BMI >30kg/m2
patients on chronic pain medication
any severe perioperative complications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To investigate duration of analgesia of ACB using ropivacaine with and without dexmedetomidine after unilateral TKR in first 24 hrs ,both at rest and movingTimepoint: 6hr,12hr,18hr,24hr
- Secondary Outcome Measures
Name Time Method to evaluate opioid consumption in first 24 hours of surgeryTimepoint: 6hr,12hr,18hr,24hr