Comparison of sedation between two group of anaesthestic drugs namely dexmedetomidine with a combination of ketamine and midazolam for awake endotracheal tube introduction by using fibre optic bronchoscopy.
Not Applicable
Completed
- Conditions
- Health Condition 1: null- - Age 18-65yrs- ASA I-III- Posted for surgery under general anesthesia.- Requiring nasotracheal intubationHealth Condition 2: C01- Malignant neoplasm of base of tongue
- Registration Number
- CTRI/2018/01/011141
- Lead Sponsor
- AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1.ASA I-III
2.Posted for surgery under general anesthesia.
3.Requiring nasotracheal intubation with any of the following
i) Anticipated difficult airway based on physical examination
ii) Anticipated difficult mask ventilation
iii) Previous history of difficult intubation
Exclusion Criteria
1.Patientââ?¬•s refusal
2.BMI > 35
3.Allergy to study medication
4.History suggestive of gastro-oesophageal reflex
5.Pregnancy
6.hepatic or renal disorders
7.history of psychotropic drug intake or drug abuse
8.long term use of benzodiazepines or tricyclic antidepressants.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Difference in the cough score at the time of <br/ ><br>introduction of endotracheal tube through glottis.Timepoint: After introduction of fibre optic endoscopy into larynx ,then the endotracheal tube is inserted till the Etco2 detected in monitor .
- Secondary Outcome Measures
Name Time Method Overall intubation scores . <br/ ><br>Post intubation score. <br/ ><br>Patient satisfaction score in postoperative period. <br/ ><br>Hemodynamic parameters in both group.Timepoint: Before introduction of fibre optic endoscopy till the Induction agent is given for general anaesthesia