The role of dexmedethomidine in sedation and analgesia in the emergency department
Phase 2
- Conditions
- distal radial fracture.Injury to the wrist and hand(S60-S68)
- Registration Number
- IRCT20160401027165N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
All patients aged 18 to 60 years old who referred to the emergency department with a distal radial fracture
Exclusion Criteria
patient who taking antihypertensive or antihistaminic drugs
patient aged less than 18 years
Severe associated injury include: Head trauma and deceased level of consciousness (GCS <15), Severe chest trauma Cervical spine trauma with unstable fracture
Patients with hemodynamic instability
Patients with mental retardation
Patients with a history of heart disease (bradycardia and any AV heart block)
pregnant patient
history of allergy to midazolam, fentanyl and dexmedethomidine
addiction to opioids and substance abuse
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain. Timepoint: Before inducing sedation and analge- After the procedure and complete awakining. Method of measurement: Visual analog scale(VAS).;Hypertension. Timepoint: Before, during and immediately after the completion of procedure. Method of measurement: Electronic barometric( Saadat Factory).;Heat rate. Timepoint: Before, during and immediately after the completion of procedure. Method of measurement: Electronic Monitor( Saadat Factory).;SPO2. Timepoint: Before, during and immediately after the completion of procedure. Method of measurement: Electronic Pulsoximer( Saadat Factory).;Respiratory rate. Timepoint: Before, during and immediately after the completion of procedure. Method of measurement: Clinical examination(Obsevation).
- Secondary Outcome Measures
Name Time Method Apnea. Timepoint: during and immediately after the completion of procedure. Method of measurement: close observation.;Bradycardia. Timepoint: during and immediately after the completion of procedure. Method of measurement: Electronic Monitor( Saadat Factory).;Nausea and vomiting. Timepoint: during and immediately after the completion of procedure. Method of measurement: close obsevation.