To study the interaction of H. pylori(bacterial) infection and iron status on iron absorption from ferrous fumarate in iron deficient and iron replete young children.
Not Applicable
Completed
- Registration Number
- CTRI/2018/05/013676
- Lead Sponsor
- International Atomic Energy Agency
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. School going children.
2. Not taking any food supplements or fortified drinks.
3. Not planning to move out during the study duration.
4. H. pylori infected.
5. Iron replete (SF >15 ng/ml and ZnPP <40 umol/mol heme or TfR <8.5 mg/L, and CRP <10mg/L)
6. Iron deficient (SF <15 ng/ml and ZnPP >40umol/mol heme or TfR >8.5 mg/L, and CRP <10mg/L).
Exclusion Criteria
1. Severe anemia (Hb <8 g/dL).
2. CRP >10mg/dL
3. Cardiovascular disease on clinical examination or history.
4. Underlying respiratory disease with impairment of lung function.
5. Recent history (3 months prior) of serious infections, injuries and/ or surgeries
6. Any food allergy or food intolerance
7. Participation in any nutritional study in the last 1year
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To measure the interaction of H. Pylori infection and eradication therapy on iron absorption in school children.Timepoint: Baseline and Endline
- Secondary Outcome Measures
Name Time Method 3.To assess the impact of H. pylori on the relative bioavailability of ferrous fumarate as against ferrous sulphate.Timepoint: Baseline and Endline