A study on comparison between monetary & clinical benefit gained by stopping antibiotic therapy early in high risk type of fever with blood neutrophil count less than 500 per micro litre in children with cancer
- Conditions
- Health Condition 1: D701- Agranulocytosis secondary to cancer chemotherapy
- Registration Number
- CTRI/2020/07/026858
- Lead Sponsor
- AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1. Age 2-18 yrs
2. De novo and relapsed AML & ALL undergoing induction & reinduction with febrile neutropenia
1. Already enrolled once in previous episode
2. Retrovirus positive patients
3. Patients who require >= 3rd line antibiotics during febrile neutropenia episode prior to becoming afebrile
4. Patients who require therapeutic antifungals during febrile neutropenia episode prior to enrolment
5. Patients who require ionotropic support / mechanical ventilation during treatment course for febrile neutropenia episode prior to enrolment
6. Severe renal function impairment (defined as a creatinine clearance below 30 ml/min) during treatment course for febrile neutropenia prior to enrolment
7. The clinical or microbiological or radiologic focus of infection during treatment course for febrile neutropenia prior to enrolment
8. Patient undergone stem cell transplant
9. Denying consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method