A study on the impact of pineapple-extracted ceramide for alleviation of the symptoms of dry mouth
Phase 1
- Conditions
- xerostomia
- Registration Number
- JPRN-UMIN000022976
- Lead Sponsor
- Kagoshima University Medical and Dental Hospital
- Brief Summary
The oral moisture significantly increased and the VAS score of "How is dryness of your mouth?" significantly improved after GCP tablets intake and not after placebo tablets intake. The number of fungiform papillae was not significantly different following GCP tablets or placebo tablets intake.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
Not provided
Exclusion Criteria
Subjects who have received radiotherapy or chemotherapy. Subjects who have scheduled the extraction of teeth or the other oral surgical management. Subjects who have a history of allergic reaction with pineapple and fruit.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Subjective evaluation of dry mouth at before administration and two weeks after administration
- Secondary Outcome Measures
Name Time Method Moisture level, saliva wetness and number and form of fungiform papilla at before administration and two weeks after administration